What exactly is NMN?
NMN stands for nicotinamide mononucleotide, a natural molecule contained in all species. About the molecular level, it’s a ribonucleotide, a simple structural unit with the nucleic acid RNA. It includes a nicotinamide group, a ribose, as well as a phosphate group.
NMN is a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule that could be attractive slowing some facets of aging. NAD+ serves many critical functions in our cells, for example electron transport, cell signaling, and DNA repair.
Accumulating evidence implies that as our bodies age, our numbers of NAD+ decline, increasing our likelihood of age-related diseases.
This is how the NAD+ precursor NMN also comes in. Some researchers believe when we can restore that lost NAD+, we will not merely slow down aging but additionally delay various age-related diseases. Whether restoring NAD+ metabolism in humans will slow aging or support healthy longevity continues to be an unanswered question, although the animal data is promising.
What foods contain NMN?
NMN can be found naturally in foods including avocado, broccoli, cabbage, cucumber, and edamame. Here’s how much NMN is situated in some common foods.
While most of these foods are loaded with nutrition, dietary NMN supplements can also be found. These supplements typically come in doses which can be between 100 – 500 mg, although an ideal dose has not determined in people.
Fasting and caloric restriction also may actually increase NAD+ levels and improve the activity of sirtuins, aka the longevity genes. It is strongly recommended that the activity relies upon the presence of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, also it appears to slow aging.
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