Search engine for touristic excursions to any place in the world SINCE The second world war, medical science has progressed into a stage where competitive medications are around to treat the same ailment in several people. It’s not just about brands (the industry trade issue) but generic drugs (the industry scientific issue). With this report, we shall glance at the various factors that decide your selection of a selected drug.
Safety: The following sub-criteria has to be considered under the criterion of safety:
* Acute therapeutic index: If your patient’s condition is acute, how effective can be a particular drug even if they have certain side-effects so long as the acuteness from the condition is lowered? Example: narcotic pain-killers are amazing in healing pain but come with the possible side-effect of addiction.
* Long-term safety: medication directory could be safe in short-term treatment, but wait, how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but can have undesirable effects in the case of prolonged use.
* Drug-drug interaction risk: Drugs are chemicals, and a lot of chemicals react to create a different chemical, which has an effect which could harm the patient or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.
Drug-drug interaction risk is of two types:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, independent of each other, have certain effects using one or more body processes (e.g., metabolism) that affects the performance from the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is dependent upon due to the metabolism. This makes more the side-effects of Lexapro.
· Pharmacodynamic: Here, two or more drugs actually produce the same relation to the same organ, thus enhancing the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly on the brain. Thus, the side-effects of the two medicine is more serious.
Tolerability: A medication could be effective however, not tolerable by all patients. Example: Allergies to certain drugs in a few people. Short-term and long-term tolerability should be taken into account. Efficacy: A medication is just not equally good at all patients. By way of example, some patients with depression or anxiety disorders experience relief from escitalopram, but there are many that do not, who therefore should be prescribed an alternative anti-depressant. The pace of start of therapeutic action is an important key to be looked at too.
Cost: Cost does not always mean the expense of buying a specific medicine alone. It should also cover the expense of treatment of a complication which could arise from using an alternative drug. Example: In the person who insists on taking alcohol yet needs to be treated for depression is usually administered an SSRI drug because these drugs don’t potentiate the results of alcohol, whereas another number of anti-depressants (such as tricyclics) can cause a fresh problem in such patients, which will need a different and expensive treatment. Therefore, it’s easier to prescribe the more expensive escitalopram rather than cheaper tricyclic in this patients.
Simplicity of treatment: Most effective mode of administration is preferred. When there is an option between an injection and oral administration, the latter is preferred if your efficacy of the two modes is analogous. Or, local application is chosen over the oral route where possible; e.g., antibiotic treatment of eye infections. Dosage and frequency of administration too are key point to make a decision simple treatment.
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