Search engine for touristic excursions to any place in the world SINCE World War II, medical science has progressed to some stage where competitive medications are around to treat precisely the same ailment in various people. It’s not nearly brands (that is a trade issue) but generic drugs (that is a scientific issue). On this report, we shall look at the various factors that decide your selection of a selected drug.
Safety: These sub-criteria must be considered within the criterion of safety:
* Acute therapeutic index: When the patient’s condition is acute, how effective is a particular drug even though they have certain side-effects as long as the acuteness with the condition is lowered? Example: narcotic pain-killers work well in healing pain but feature the opportunity side-effect of addiction.
* Long-term safety: drug may be safe in short-term treatment, but how safe it really is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but can have undesirable effects in the event of prolonged use.
* Drug-drug interaction risk: Prescription medication is chemicals, and several chemicals reply to develop a different chemical, that have an effect that may harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.
Drug-drug interaction risk is of two sorts:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, outside of the other person, have certain effects one or more body processes (e.g., metabolism) that affects the performance with the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is dependent upon due to the metabolism. This will cause a rise in the side-effects of Lexapro.
· Pharmacodynamic: Here, a couple of drugs actually produce the same influence on precisely the same organ, thus helping the total, added effect. Example: Lexapro has certain side-effects for example drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of both the medicine is more serious.
Tolerability: A medication may be effective although not tolerable by all patients. Example: Allergies to particular drugs in some people. Short-term and long-term tolerability should be taken into consideration. Efficacy: A medication is not equally effective in all patients. For example, some patients with depression or anxiety disorders experience reduced escitalopram, but there are lots of that don’t, who therefore should be prescribed another anti-depressant. The pace of beginning of therapeutic action is a the answer to be regarded too.
Cost: Cost does not necessarily mean the cost of acquiring a certain medicine alone. It will also cover the cost of treatment of a complication that may arise by using another drug. Example: In a person who insists on taking alcohol nevertheless needs to be treated for depression is often administered an SSRI drug as these drugs don’t potentiate the consequences of alcohol, whereas another gang of anti-depressants (for example tricyclics) might cause a new overuse injury in such patients, which could demand a various and expensive treatment. Therefore, it’s preferable to prescribe the more costly escitalopram rather than cheaper tricyclic in these patients.
Simple treatment: The simplest mode of administration is preferred. If you have an alternative between an injection and oral administration, aforementioned is preferred in the event the efficacy of both the modes is comparable. Or, local application is preferred to the oral route where possible; e.g., antibiotic treatment of eye infections. Dosage and frequency of administration too are a key factor to determine simplicity of treatment.
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