Search engine for touristic excursions to any place in the world SINCE World War II, medical science has progressed to some stage where competitive medications are available to treat exactly the same ailment in various people. It’s not nearly brands (that is a trade issue) but generic drugs (that is a scientific issue). In this report, we shall consider the various factors that decide picking a a selected drug.
Safety: These sub-criteria should be considered beneath the criterion of safety:
* Acute therapeutic index: In the event the patient’s condition is acute, how effective can be a particular drug even though it has certain side-effects so long as the acuteness in the condition is lowered? Example: narcotic pain-killers work well in healing pain but feature the possible side-effect of addiction.
* Long-term safety: drug directory could possibly be safe in short-term treatment, so how safe it can be in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but can have undesirable effects in case there is prolonged use.
* Drug-drug interaction risk: Drugs are chemicals, and lots of chemicals respond to produce a different chemical, which has an effect that may harm the patient or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.
Drug-drug interaction risk is of two sorts:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, outside of each other, have certain effects on a single or even more body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) is dependent upon due to the metabolism. This will cause a rise in the side-effects of Lexapro.
· Pharmacodynamic: Here, two or more drugs actually make the same relation to exactly the same organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of both prescription medication is more intense.
Tolerability: A drug could possibly be effective however, not tolerable by all patients. Example: Allergies to particular drugs in some people. Short-term and long-term tolerability have to be looked at. Efficacy: A drug is just not equally good at all patients. For instance, some patients with depression or panic disorders experience respite from escitalopram, but there are numerous that do not, who therefore have to be prescribed some other anti-depressant. The pace of onset of therapeutic action is an important factor to be regarded as too.
Cost: Cost does not necessarily mean the cost of purchase of some medicine alone. It ought to also cover the cost of treating a complication that may arise from using some other drug. Example: In a individual who insists on taking alcohol but must be treated for depression is usually administered an SSRI drug because these drugs don’t potentiate the results of alcohol, whereas another group of anti-depressants (such as tricyclics) could cause a whole new overuse injury in such patients, which will require a various and expensive treatment. Therefore, it’s safer to prescribe the more costly escitalopram rather than a cheaper tricyclic in these patients.
Simplicity of treatment: The best mode of administration is preferred. If you have a selection between an injection and oral administration, aforementioned is preferred if your efficacy of both modes is the identical. Or, local application is chosen over the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are an important factor to make a decision simple treatment.
Check out about drug directory you can check our new resource: read